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Clinical Evidence: Muscle Preservation in Trials Phase 3 Lean Mass Data Retatrutide (23.9% weight loss): Lean mass loss: ~5.2% of body weight Lean mass as % of total loss: 21.8% Fat loss: 78.2% of total weight lost Tirzepatide (20.9% weight loss): Lean mass loss: ~6.8% of body weight Lean mass as % of total loss: 32.5% Fat loss: 67.5% of total weight lost Translation : At 220 lbs body weight with 26 lbs weight loss: Retatrutide achieves 2.5x better muscle preservation than semaglutide

doi: 10.1371/journal.pone.0035683 [DOI] [PMC free article] [PubMed] [Google Scholar] 62.Thompson A, Kanamarlapudi V

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Two (50%) participants were on one T2D medication and two (50%) were on two T2D medications

GLP-1 lalarnn zellikleri GLP-1 etkili ilalar, tbbi tedavi kapsamnda deerlendirilir