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A lack of folate is linked to double-strand mutations in DNA replication

(8) CoQ 10 synthesis and cellular distribution in the regulation of ferroptosis CoQ2 and STARD7: key regulators and therapeutic targets in ferroptosis modulation Cellular resistance to ferroptosis may depend not only on maintaining a robust pool of ubiquinol (CoQ 10 H 2 ) but also on the overall size of the cellular CoQ 10 pool

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L.WhelanR

Trop Med Infect Dis

However, in other rodents or mammals, selenocysteine cannot be synthesized due to the lack of selenocysteine insertion sequences in related genes, and it is a non-selenium protein replaced by cysteine (Cys) (Brigelius-Floh and Maiorino, 2013)