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Betaine is a choline-derived metabolite and a methyl group donor with antioxidant, anti-inflammatory and osmoprotectant properties

McMillan, K

This unexpected effect of PQQ was reversed by catalase, indicating that it completely eradicated the production of H 2 O 2 during PQQ autoxidation in the culture medium

In addition, the KD reduced endoplasmic reticulum (ER) stress, protein synthesis, and proteasome activity, suggesting a decrease in protein turnover and a reduction in overall cellular stress [114]