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Retatrutide in Thailand: Triple-Agonist Therapy Retatrutide (LY3437943) is an investigational triple-agonist peptide that simultaneously targets GLP-1, GIP, and glucagon receptors: the three pathways that together govern appetite, energy expenditure, and metabolic rate

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While stepping up your dose may trigger brief mild nausea as your body re-adapts, the nausea is usually shorter and less intense than your initial experience because you've already built tolerance to the medication's core mechanism

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