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Moreover, pharmacokinetic evaluations reveal that AOD 9604 has a short plasma half-life of about three to four minutes intravenously and slower absorption when administered orally

Deamidation-prone residues Asparagine Glutamine These degrade faster in moisture or in solution at higher temperatures

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2.5 Effect of phosphorylation -synuclein recovered from Lewy bodies of patients affected with sporadic Parkinsons disease and LBD as well as from glial cytoplasmic inclusion bodies in oligodendrocytes of patients affected with Multiple System Atrophy has been found to be heavily phosphorylated in the 129th serine residue of the C terminal domain (Ghanem et al., 2022)

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